BIOGRAPHICAL SKETCH Provide the following information for the key personnel in the order listed for Form Page 2. Photocopy this page or follow this format for each person.
NAME Chris Meichung Wang Ho		POSITION TITLE Chief Executive Officer Drug Design Methodologies, L.L.C.
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION	DEGREE (if applicable)		YEAR(s)	FIELD OF STUDY
Purdue University, West Lafayette, IN.	B.S.		1987	Biology
Washington University School of Medicine St. Louis, MO	M.D. Ph.D.		1996	Medicine, Pharmacology

Professional Experience:
1990-1999 Teaching Assistant, Washington University
1996-Present Consultant: Computer aided drug design specialist -Pfizer Pharmaceutical Research,
Pharmacia, and Tripos Associates.
1996-Present CEO, Drug Design Methodologies, LLC.

Awards and Other Professional Activities:
Medical Scientist Training Program - Washington University M.D.Ph.D. program (full tuition & stipend)
Spencer T. and Ann W. Olin fellow, Washington University, St. Louis, MO.
Purdue University Class of 1987 – Valedictorian

Selected Relevant Publications:

1. Ho, C.M.W. and Marshall, G.R., “CAVITY SEARCH: An Algorithm for the Isolation and Display of Cavity-like Binding Regions,” J. Comp. Aided Molec. Design, (1990) 4:337-354.

2. Ho, C.M.W. and Marshall, G.R., “FOUNDATION: A Program to Retrieve All Possible Structures Containing a User-Defined Minimum Number of Matching Query Elements from Three-Dimensional Databases,” J. Comp. Aided Molec. Design, (1993) 7:3-22.

3. Ho, C.M.W. and Marshall, G.R., “SPLICE: A Program to Assemble Partial Query Solutions from Three-Dimensional Database Searches into Novel Ligands,”J. Comp. Aided Molec. Design, (1993) 7:623-647.

4. Ho, C.M.W. and Marshall, G.R., “Denovo Design of Ligands,” Proceedings of the 27^th Annual Hawaii International Conference on System Sciences – Vol. V: Biotechnology Computing, IEEE Comp. Soc. Press, (1994) 213-222.

5. Ho, C.M.W. and Marshall, G.R., “DBMAKER: A Set of Programs to Generate Three-Dimensional Databases Based Upon User-Specified Criteria,” J. Comp. Aided Molec. Design, (1995) 9:65-86.

6. Oprea, T.I., Ho, C.M.W. and Marshall, G.R., “De Novo Design: Ligand Construction and Prediction of Affinity,” in Computer-Aided Molecular Design – Applications in Agrochemicals, Materials, and Pharmaceuticals. ACS Symposium Series 1995, Reynolds, C.H., Holloway, M.K. and Cox, H.K.

7. Marshall, G.R., Ho, C.M.W., Head, R.D., Smythe, M.L., Oprea, T.I., Waller, C.L., and Green, S.M., “3D QSAR and De Novo Design: Choosing the Appropriate Tools,” in QSAR and Molecular Modelling: Concepts, Computational Tools, and Biological Applications, F. Sanz, J. Giraldo, and F. Manaut, Eds., Prous Science Publishers, Barcelona, Spain (1995) 623-629.