| Defined
Component #1 |
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| Defined
Component #1: |
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| 1. Must contain ring structures – five to six atoms in size. |
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| 2. One or more hydrogen bond donor groups must be present. |
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| 3. Component must hydrogen bond to Asp 189 (pharmacophore) |
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| © 2003 Drug
Design Methodologies, L.L.C. |